Just in case you missed it, there was a good post from Up and Ready on Friday about an issue affecting the Sheet Set Manager when using DWG files stored on Windows 2008 R2 servers running with SMB V2.
Network performance issue when using SMB Ver. 2
Up and Ready is a newcomer among the Autodesk Product Support blogs and they have a lot of useful information to share. If you aren't already following them, you should.